A Complete Guide to Fucoidan
Fucoidan is a complex polymer present in many brown seaweed species. It possesses antiviral and immune-modulating properties, as well as the ability to stop cancer cells from growing. The scientific literature on Fucoidan is quickly expanding, owing to the wide range of biological activity found in brown seaweed. Fucoidan has been shown to inhibit the proliferation of cancer cells.
Main Working Mechanism
With the help of reduced expression and metalloprotein secretion, fucoidan helps to cause apoptosis. The binding activity of NF-kappaB is suppressed as a result of this. Similarly, fucoidan protects against liver injury by suppressing enzymes. The pathway is inhibited by inflammatory signals. Dietary fucoidan reduces the time it takes for the thrombus to dissolve. It induces an increase in blood water production by increasing prostacyclin secretion. In melanoma cells, the effects of lapatinib are amplified. It aids in the induction of apoptosis in the type of leukemia virus that is generated by adult T-Cell.
Fucoidan is the safest brown seaweed. The majority of research imply that fucoidan is useful to us in a variety of ways, including reducing inflammation, treating carcinogens, and reducing oxidative stress. Fucoidan is used in skincare and animal feed supplements. It is becoming increasingly important for the use of dietary supplements. In most of these researches, fucoidan crude extract is used, which has an impact on the evaluation of bioactivities. New fucoidan-based pharmaceutical products are being developed for the treatment of cardiovascular disease and are being evaluated for human safety before being used. A daily 400 mg consumption of fucoidan was studied in Japan, where people eat a lot of seaweed and hence include fucoidan in their diets, and it had no negative effects.
Fucoidan and Cancer:
The ability of fucoidan to interact with other anti-cancer chemicals has only lately been found. Fucoidan inhibited the migration of multiple myeloma cells treated with chemotherapeutic agents. The anti-tumor effect of low-dose polyphenols was discovered to synergize with fucoidan from Saccharina chlorimides. With the help of fucoidan, the colony number was reduced by 60% in the colony formation assay, compared to 34% and 27% in resveratrol alone. Colorectal cancer is also one of the most frequent cancers worldwide. Fucoidan was tested on the human colon cancer DLD-1 and found to prevent tumor cell multiplication by decreasing the activity of epidermal growth factors, according to Vishchuk et al. Apoptosis was investigated by Kim et al. They discovered that the loss of receptor-mediated induction of apoptosis regulates the apoptosis of colon cancer cells produced by fucoidan.
The Final Takeaway!
Our sea fucoidan is a high-quality seaweed extract that is currently the finest on the market. Every bottle is loaded with an assured high extract based on clinical examinations. For almost 25 years, we've been producing fucoidan. Our extraction method ensures that the extract is free of chemicals and satisfies WHO safety standards. Because our fucoidan has a molecular mass, it is more easily absorbed by the elderly and those with weak stomachs.